Publicaciones

  • Amyloid beta precursor protein as a molecular target for amyloid ?–induced neuronal degeneration in Alzheimer’s disease. Bignante EA, Heredia F, Morfini G, Lorenzo A. Neurobiol Aging. 2013 Nov;34(11):2525-37. doi: 10.1016/j.neurobiolaging.2013.04.021.
  • Axonal transport of APP and the spatial regulation of APP cleavage and function in neuronal cell.s Brunholz S, Sisodia SS, Lorenzo A, Deyts C, Kins S, Morfini G. (2011).  Exp. Brain Res., 2011 Sep 30. Review
  • Comparative analyses of the neurodegeneration induced by the non-competitive NMDA receptor antagonist drug MK801 in mice and rats.  Bender C, de Olmos S, Bueno A, de Olmos J, Lorenzo A (2010).  Neurotoxicol Teratol, 32, 542-550.
  • Involvement of AMPA/Kainate-excitotoxicity in MK801-induced neuronal death in the retrosplenial cortex. Bender C, Rasetto M, de Olmos JS, de Olmos S, Lorenzo A. (2010).  Neuroscience 169, 720-732. (IF2008: 3,556 – cit: 0)
  • Secreted-APP and holo-APP bind Amyloid b through distinct domains eliciting different toxic responses on hippocampal neurons.  Kedikian G, Heredia F, Rozes Salvador V, Raimunda D, Isoardi N, Heredia L, Lorenzo A.  (2010) J. Neurosci. Res 88(8), 1795-1803.
  • Cryopreservation of cortical tissue blocks for the generation of highly enriched neuronal cultures.Rahman A, Parvinjah S, Hanna M, Helguera P, Coskun P and Busciglio J. (2010).  J Vis Exp, , 45: 2384 [pii]
  • Neurodegeneration and prolonged immediate early gene expression throughout cortical areas of the rat brain following acute administration of MK801.  de Olmos S, Bender C, de Olmos JS, Lorenzo A. (2009). Neuroscience 164, 1347–1359.
  • Amyloid beta Precursor protein mediates neuronal toxicity of Amyloid beta fibrils through Go protein activation.  Solá Vigo F, Kedikian G, Heredia L, Heredia F, Díaz Añel A, Lorenzo A. (2009).  Neurobiol. Aging 30(9), 1379-1392.
  • Sex differences and influence of gonadal hormones on MK801-induced neuronal degeneration in the granular retrosplenial cortex of the rat.  de Olmos S, Bueno A, Bender C, Lorenzo A, de Olmos J. (2008).  Brain Struct. Funct. 213(1-2):229-238.
  • Estrogen receptor a is expressed on the cell-surface of embryonic hypothalamic neurons.  Gorosito SV, Lorenzo A, Cambiasso MJ. (2008).  Neuroscience 154, 1173-1177.
  • Role of LIMK1 in neuronal degeneration in Alzheimer´s Disease.  Lorenzo A and Heredia L. (2008), pp39-49. In “Neurodegenerative Diseases: From Molecular Concepts to Therapeutic Targets” Editors Rommy von Bernhardi and Nibaldo Inestrosa.  Nova Science Publishers Inc, New York (ISBN 978-1-60456-167-8)
  • Phosphorylation of ADF/Cofilin by LIM-kinase mediates Amyloid beta-induced degeneration: a potential mechanism of neuronal dystrophy in Alzheimer´s disease.  Heredia L, Helguera P, de Olmos S, Kedikian G, Solá Vigo F, LaFerla F, Staufenbiel M, de Olmos J, Busciglio J, Cáceres A,  Lorenzo A. (2006).  J. Neurosci. 26(24):6533-6542.
  • Amyloid beta-induced neurodegeneration promotes cell surface accumulation of Amyloid-beta Precursor protein. Heredia L., Lin R, Solá Vigo R, Kedikian R, Busciglio J and Lorenzo A. (2004).  Neurobiol. Dis. 16(3):617-629.
  • Amyloid beta interacts with the amyloid precursor protein: a potential toxic mechanism in Alzheimer’s disease.  Lorenzo A, Yuan M, Zhang Z, Paganetti PA, Sturchler-Pierrat C, Staufenbiel M, Mautino J, Vigo FS, Sommer B, Yankner BA. (2000).  Nature Neurosci. 3(5):460-464.